- A Case of Advanced Hepatocellular Carcinoma Treated with Curative Surgical Resection after Downstaging by Hepatic Arterial Infusion Chemotherapy
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Jong Ryul Eun, Heon Ju Lee, Jae Woon Kim, Jay Chun Chang, Sung Su Yun, Joon Hyuk Choi
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Journal of the Korean Liver Cancer Study Group. 2011;11(1):60-64. Published online February 28, 2011
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Abstract
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- Cure by single modality for advanced hepatocellular carcinoma (HCC) is difficult. Therefore, multidisciplinary approaches are
needed to get a better outcome for advanced HCC. In this paper, we report a case of advanced HCC treated with curative surgical
resection after downstaging by hepatic arterial infusion chemotherapy (HAIC). A 50-year-old male patient had a maximum 16.0
cm sized HCC in the right lobe. He achieved a partial response after 2 cycles of HAIC with 5-FU (750 mg/m2) and cisplatin (25
mg/m2). After completion of 6 cycles, he received a curative right hepatectomy and the histopathology revealed 95% of tumor
necrosis. He is under follow-up without recurrence at 14 months of surgery. This case suggests that surgery after downstaging by
HAIC may provide good clinical outcome in advanced HCC.
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